(1) ToxChemMap. A tool to visualize toxicological and physicochemical properties of EU relevant chemicals
[...Under construction...]
This tool provides a framework to explore physicochemical, human toxicological and ecotoxicological properties
of hundred of thousands of chemicals relevant in the EU context.
(2) HypCCAtlas. A functional hypothalamic atlas of cell-cell communication
[...Under construction...]
HypCCAtlas is an interactive web-based tool to explore and infer cell-cell communication signals using scRNAseq datasets.
(3) ExPCom. A tool to infer cell-cell communnication using scRNAseq datasets
This repository provides a tool to infer cell-cell communnication using a scRNAseq dataset. ExPCom allows to
replicate the analysis found in Brunner et al. (2024). The functions calculate communication scores for any
set of ligand-receptor pairs (e.g. CellChat Database) based on expression product. The L*R expression product
method allows to obtain a continuous value by multiplying all possible combinations of the expression of both
interacting molecules between two given cell types.
(4) DPGEA. A Differential Pseudospatial Gradient Expression Analysis for scRNAseq data
This repository provides a framework to explore scRNAseq datasets displaying pseudospatial distributions.
The function calculates Differential Pseudospatial Gradient Expression (DPGEA) as transitional points
within the pseusopace calculated using Monocle3. DPGEA allow to replicate the analysis available in
Brunner et al. (2024) to identify tanycyte/ependyma specific and overlaping markers.
